PGT-A

What is PGT-A?

PGT-A, preimplantation genetic testing for aneuploidies, is a genetic test performed on embryos created through IVF to screen for chromosomal abnormalities. PGT-A, formerly known as preimplantation genetic screening (PGS), is used to screen embryos for extra or missing chromosomes. Embryos with extra or missing chromosomes, referred to as aneuploid, often fail to implant and lead to miscarriage or, if implantation is successful, lead to the birth of a child with a genetic condition. Embryos found to be chromosomally normal are referred to as euploid and are the most likely to lead to a successful pregnancy.

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With PGT-A, embryos without any detectable missing or extra chromosomes are selected for transfer. PGT-A may:

  • Increase the chances of implantation and pregnancy
  • Reduce the risk of miscarriage
  • Reduce the number of IVF cycles needed to achieve pregnancy
  • Increase the chances of giving birth to a healthy baby
  • PGT-A is appropriate for the vast majority of IVF patients and is recommended for:
    • Women who are over the age of 35
    • Women who have experienced one or more pregnancy losses
    • Women who have had a pregnancy with chromosomal abnormalities
    • Women who have experienced unsuccessful IVF cycles
    • Couples who want to balance the genders in their family
    • Couples challenged by male infertility factor